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Background
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
Product overview
Product Name
Suppressor of tumorigenicity 14 protein
Code
E6235Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.032ng/mL
Reactivity
Human
Detection range
0.032ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
ARCI11;CAP3;HAI;Matriptase;Membrane-type serine protease 1;MTSP1;MT-SP1;Prostamin;Serine protease 14;Serine protease TADG-15;SNC19;ST14;Suppressor of tumorigenicity 14 protein;TADG15;TMPRSS14;Tumor-associated differentially-expressed gene 15 protein
