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Background
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Product overview
Product Name
Sodium/Potassium/Calcium Exchanger 2
Code
E2540Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.012ng/ml
Reactivity
Human
Detection range
0.012ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Na(+)/K(+)/Ca(2+) exchange protein 2 antibody;NCKX2;Retinal cone Na Ca+K exchanger antibody;Retinal cone Na+/Ca+/K+ exchanger antibody;SLC24A2;Sodium/potassium/calcium exchanger 2 antibody
