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Background
Required for pre-mRNA splicing as component of the spliceosome (PubMed:29360106).
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3’end of the CCND1 gene and its mRNA.
Product overview
Product Name
Smad nuclear-interacting protein 1
Code
E6180Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.78ng/L
Reactivity
Human
Detection range
9.78ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
FHA domain-containing protein SNIP1;PML1;PMRED;Smad nuclear-interacting protein 1;SNIP1
