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Background
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
Product overview
Product Name
Secreted Frizzled Related Protein 3
Code
E3897Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.021ng/ml
Reactivity
Human
Detection range
0.021ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Frezzled;Fritz;Frizzled-related protein 1;FRZB;FrzB-1;Secreted frizzled-related protein 3;sFRP-3
