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Background
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed: 30771381). Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Product overview
Product Name
Ras-Related Protein Rab-27A
Code
E6059Hu
Assay type
Sandwich
Size
96 test
Sensitivity
8.94ng/L
Reactivity
Human
Detection range
8.94ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
GTP-binding protein Ram;RAB 27A;Rab-27;RAB27A;Ras-related protein Rab-27A
