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Home / Elisa Kits / BT LAB / Human N-lysine Methyltransferase Smyd2, SMYD2 ELISA Kit, E5782Hu

Human N-lysine Methyltransferase Smyd2, SMYD2 ELISA Kit, E5782Hu

Product Summary

  • Size: 96 test
  • Sensitivity: 7.18ng/L
  • Detection range: 15-3000ng/L
  • Sample type: Serum, plasma, cell culture supernates
  • Reactive with: Human

Ordering Information

  • Code: E5782Hu
  • Size: 96 test

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Background

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 ‘Lys-4’ (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates ‘Lys-370’ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at ‘Lys-860’.

Product overview

  • Product Name
  • N-lysine methyltransferase SMYD2
  • Code
  • E5782Hu
  • Assay type
  • Sandwich
  • Size
  • 96 test
  • Sensitivity
  • 7.18ng/L
  • Reactivity
  • Human
  • Detection range
  • 7.18ng/L
  • Sample type
  • Serum, plasma, cell culture supernates
  • Synonyms
  • Histone methyltransferase SMYD2;HSKM-B;KMT3C;Lysine N-methyltransferase 3C;N-lysine methyltransferase SMYD2;SET and MYND domain-containing protein 2;SMYD2;ZMYND14
  • Mass
  • 49,688
  • Standard Solution
  • 3200ng/L
  • Species
  • Human
  • Storage
  • 2-8ºC
  • Assay time
  • 1h 30m
  • Assay time
  • 1h 30m
  • UniProt accession
Q9NRG4
  • GeneID
  • 56950
  • Gene names
  • SMYD2
  • Research area
  • Epigenetics and Nuclear Signaling
  • Applications
  • ELISA
  • Target protein
  • SMYD2
Related Resources
Protocol Booklet
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