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Background
Component of a protein kinase signal transduction cascade (PubMed: 9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed: 9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed: 17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed: 9808624).
Product overview
Product Name
Mitogen Activated Protein kinase 1
Code
E2492Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.55ng/L
Reactivity
Human
Detection range
9.55ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
MAP3K1;MAPK/ERK kinase 1;MEK kinase 1;MEKK 1;Mitogen-activated protein kinase kinase 1
