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Background
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Product overview
Product Name
Mannose-Binding Protein C
Code
E4304hu
Assay type
Sandwich
Size
96 test
Sensitivity
2.41ng/ml
Reactivity
Human
Detection range
2.41ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Collectin-1;Mannan-binding protein;Mannose-binding lectin;Mannose-binding protein C;MBL 2;MBL2;MBP1;MBP-C
