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Background
Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Product overview
Product Name
Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3
Code
E5574Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.023ng/mL
Reactivity
Human
Detection range
0.023ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD85e;CD85 antigen-like family member E;ILT-6;Immunoglobulin-like transcript 6;Leukocyte immunoglobulin-like receptor 4;Leukocyte immunoglobulin-like receptor subfamily A member 3;LILRA 3;LILRA3;LIR-4;Monocyte inhibitory receptor HM43/HM31
