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Background
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Product overview
Product Name
Klotho Beta
Code
E2782Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.29nmol/L
Reactivity
Human
Detection range
0.29nmol/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
BetaKlotho;Beta-klotho;BKL;KLB;Klotho beta-like protein