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Background
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Product overview
Product Name
Interleukin-22 Receptor Subunit Alpha-1
Code
E5516Hu
Assay type
Sandwich
Size
96 test
Sensitivity
16.26ng/L
Reactivity
Human
Detection range
16.26ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CRF2-9;Cytokine receptor class-II member 9;Cytokine receptor family 2 member 9;IL 22RA1;IL-22 receptor subunit alpha-1;IL22RA1;IL-22RA1;IL-22R-alpha-1;Interleukin-22 receptor subunit alpha-1;ZcytoR11
