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Background
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed: 9792649, PubMed: 14528293, PubMed: 25500532). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
