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Background
Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (PubMed: 8626725, PubMed: 14528293, PubMed: 25261253, PubMed: 25500532). Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).
Product overview
Product Name
Interleukin-18 Receptor 1
Code
E5514Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.026ng/ml
Reactivity
Human
Detection range
0.026ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD218a;CD218 antigen-like family member A;CDw218a;IL 18R1;IL1 receptor-related protein;IL18R1;IL-18R1;IL-18R-1;IL-18Ralpha;IL-18R-alpha;IL1R-rp;IL-1Rrp;Interleukin-18 receptor 1;Interleukin-18 receptor alpha
