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Background
RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript ‘caging’ into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5′-UTR of the Insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.
Product overview
Product Name
Insulin-like Growth Factor 2 Mrna-Binding Protein 2
Code
E5473Hu
Assay type
Sandwich
Size
96 test
Sensitivity
33.25ng/L
Reactivity
Human
Detection range
33.25ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Hepatocellular carcinoma autoantigen p62;IGF2 mRNA-binding protein 2;IGF2BP2;IGF-II mRNA-binding protein 2;IMP-2;Insulin-like growth factor 2 mRNA-binding protein 2;VICKZ family member 2