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Background
Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.
Product overview
Product Name
Gremlin 2
Code
E7362Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.04ng/L
Reactivity
Human
Detection range
7.04ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;GREM 2;GREM2;Gremlin-2;Protein related to DAN and cerberus
