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Human Glutaredoxin-related Protein 5, Mitochondrial, GLRX5 ELISA Kit

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Background

Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed: 20364084, PubMed: 23615440). Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (PubMed: 20364084, PubMed: 23615440, PubMed: 24334290). Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed: 20364084).

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