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Human Estradiol 17-beta-dehydrogenase 8, HSD17B8 ELISA Kit

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Background

NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed: 17978863). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed: 19571038, PubMed: 25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed: 25203508).

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