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Background
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Product overview
Product Name
Engulfment and Cell Motility Protein 1
Code
E4764Hu
Assay type
Sandwich
Size
96 test
Sensitivity
10.48ng/L
Reactivity
Human
Detection range
10.48ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ELMO 1;ELMO1;Engulfment and cell motility protein 1;Protein ced-12 homolog
