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Background
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3′-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed: 14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).
Product overview
Product Name
Cleavage and Polyadenylation Specific Factor 1
Code
E2465Hu
Assay type
Sandwich
Size
96 test
Sensitivity
4.46ng/L
Reactivity
Human
Detection range
4.46ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Cleavage and polyadenylation specificity factor 160 kDa subunit;Cleavage and polyadenylation specificity factor subunit 1;CPSF 1;CPSF 160 kDa subunit;CPSF1
