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Background
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Product overview
Product Name
Bcl2 Antagonist of Cell Death
Code
E4102hu
Assay type
Sandwich
Size
96 test
Sensitivity
2.42ng/L
Reactivity
Human
Detection range
2.42ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
BAD;Bcl2 antagonist of cell death;Bcl2-associated agonist of cell death;Bcl-2-binding component 6;Bcl2-L-8;Bcl-2-like protein 8;Bcl-xL/Bcl-2-associated death promoter
