Human CD63 antigen, also referred to as Granulophysin, Lysomal-associated membrane protein 3 (LAMP-3), Tetraspanin-30, and Ocular melanoma-associated antigen, is a membrane bound protein encoded by the gene CD63. CD63 belongs to a group of proteins known as the tetraspanin family, which are characterized by the presence of four hydrophobic domains and are found to mediate signal transduction events for the regulation of cell development, activation, growth, and motility. Deficiency of this protein is associated with Hermansky-Pudlak Syndrome, which is an autosomal disorder.
Human CD163 antigen, CD163 ELISA Kit, E0246Hu
CD163 is a scavenge receptor for the haptoglobin-hemoglobin complex. CD163 clears the complex in the liver, spleen and circulation. Soluble CD163 also plays a role in reducing inflammation, and dysregulation of CD163 is associated with some inflammatory conditions like multiple sclerosis, rheumatoid arthritis and diabetes mellitus.
Human Vitamin H, VH ELISA Kit, E3932Hu
A B vitamin that aids in body growth.
Rabbit Vascular Endothelial cell Growth Factor, VEGF ELISA Kit, E0026Rb
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Human Vascular Endothelial cell Growth Factor, VEGF ELISA Kit, E0080Hu
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Human Vitamin D Receptor, VDR ELISA Kit, E1553Hu
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Rat Vitamin C, VC ELISA Kit, E0612Ra
A vitamin found in fresh fruits (especially citrus fruits) and vegetables; prevents scurvy.
Human Visceral adipose-specific serine protease inhibitor, vaspin ELISA Kit, E0921Hu
May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues.
Human Tumour necrosis factor related weak inducer of apoptosis, TWEAK ELISA Kit, E1820Hu
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
Human Trimethylamine-N-oxide reductase, TorA ELISA Kit, EA0141Hu
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.