Vitamin D Binding Protein, also known as gc-globulin, is a 458 – amino acid, glycosylated protein encoded by the gene GC, which is in the albumin gene family. The primary function of this protein is to bind Vitamin D and its metabolites and to transport them to tissue. Vitamin D Binding protein is highly expressed and secreted into serum primarily from hepatic cells. There are three common alleles of the protein (Gc1f, Gc1s, and Gc2), and several minor polymorphisms. Different glycosylation sites are found on the isoforms of Vitamin D binding protein, a selectively deglycosylated form produced by B cell ß-galactosidase and T cell sialidase is known as Macrophage Activating Factor. MAF has been found to block angiogenic effects of several proteins on vascular endothelial cells.
Rat Dopamine D2 receptor, D2R ELISA Kit, E0221Ra
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Rat Cross Linked C-telopeptide of Type 1 Collagen, CTX-1 ELISA Kit, E1146Ra
The degradation product oftypelcollagen.
Human Cross Linked C-Telopeptide of Type 1 Collagen, CTX-1 ELISA Kit, E3700Hu
The degradation product oftypelcollagen.
Human Complement C1q tumor necrosis factor-related protein 3, CTRP3 ELISA Kit, E3300Hu
C1q/TNF-related protein 3 (CTRP3) represents an adipokine with various metabolic and immune-regulatory functions.
Human Chondroitin sulfate, CS ELISA Kit, E1895Hu
Chondroitin sulfate is mucopolysaccharides-class substance extracted from animal cartilage. It has an important role in prevention and treatment of cardiovascular disease, joint disease, and currently is an important biochemical product on the market.
Human Copeptin, CPP ELISA Kit, E1129Hu
Copeptin is a diagnostic and prognostic biomarker for cardiovascular disease (CVD). Copeptin is also the carboxyl terminus of the arginine vasopressin (AVP) precursor peptide. Copeptin can be used in the study of cardiovascular disease.
Monkey C-Peptide, C-P ELISA Kit, E0030Mk
C-peptide of insulin is a cleavage product produced during processing of the insulin pro-hormone to the mature insulin molecule. Proinsulin is cleaved when it is released from the pancreas into the blood – one C-peptide for each insulin molecule. C-Peptide has been shown to bind to a variety of cell types, and in vivo animal diabetes models have shown positive effects on kidney and nerve function.
Human Carboxymethyl Lysine, CML ELISA Kit, E1413Hu
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.
Rat Creatine Kinase MB isoenzyme, CK-MB ELISA Kit, E0311Ra
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.