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Background
Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5′-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity.
Product overview
Product Name
Mitochondrial-derived Peptide MOTS-c
Code
E6880Hu
Assay type
Sandwich
Size
96 test
Sensitivity
4.08ng/L
Reactivity
Human
Detection range
4.08ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Mitochondrial open reading frame of the 12S rRNA-c;Mitochondrial-derived Peptide MOTS-c;MTRNR1;MT-RNR1;RNR1
