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Background
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166, PubMed:22323612).
May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
Product overview
Product Name
DNA topoisomerase 2-alpha
Code
E6652Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.78ng/L
Reactivity
Human
Detection range
9.78ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;TOP2;TOP2A;TOP2alpha;TOPIIA;TP2A
