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Background
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204).
The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204).
With OSBPL3, may regulate ER morphology (PubMed:16143324).
May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470).
Product overview
Product Name
Vesicle-associated membrane protein-associated protein A
Code
E6397Hu
Assay type
Sandwich
Size
96 test
Sensitivity
8.91ng/L
Reactivity
Human
Detection range
8.91ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
33 kDa VAMP-associated protein;hVAP-33;VAMP-A;VAMP-associated protein A;VAP33;VAP-33;VAPA;VAP-A;Vesicle-associated membrane protein-associated protein A;
