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Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Product overview
Product Name
T cell immunoreceptor with Ig and ITIM domains
Code
E6245Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.019ng/mL
Reactivity
Human
Detection range
0.019ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
T-cell immunoreceptor with Ig and ITIM domains;TIGIT;V-set and immunoglobulin domain-containing protein 9;V-set and transmembrane domain-containing protein 3;VSIG9;VSTM3;WUCAM