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Background
Mediates the voltage-dependent sodium ion permeability of excitable membranes.
Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.In macrophages and melanoma cells, may participate in the control of podosome and invadopodia formation.
Product overview
Product Name
Sodium Channel protein type 8 subunit alpha
Code
E6188Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.24ng/L
Reactivity
Human
Detection range
9.24ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
BFIS5;CIAT;DEE13;EIEE13;MED;MYOCL2;NaCh6;Nav1.6;PN4;SCN8A;Sodium Channel protein type 8 subunit alpha;Sodium Channel protein type VIII subunit alpha;Voltage-gated sodium Channel subunit alpha Nav1.6;
