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Background
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
Product overview
Product Name
Rap guanine nucleotide exchange factor 4
Code
E6056Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.67ng/L
Reactivity
Human
Detection range
7.67ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CAMP-GEFII;cAMP-regulated guanine nucleotide exchange factor II;CGEF2;EPAC;EPAC 2;EPAC2;Exchange factor directly activated by cAMP 2;Exchange protein directly activated by cAMP 2;Nbla00496;Rap guanine nucleotide exchange factor 4;RAPGEF4
