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Background
Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (PubMed:21798305, PubMed:21939755).
Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity).
Product overview
Product Name
Phosphatase and actin regulator 1
Code
E5860Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.86ng/L
Reactivity
Human
Detection range
7.86ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
DEE70;dJ257A7.2;EIEE70;PHACTR1;Phosphatase and actin regulator 1;RPEL;RPEL1