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Background
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Product overview
Product Name
Melanocyte protein PMEL
Code
E5652Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.41ng/L
Reactivity
Human
Detection range
7.41ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
95 kDa melanocyte-specific secreted glycoprotein;D12S53E;gp100;M-alpha;M-beta];ME20;ME20M;ME20-M;ME20S;ME20-S;Melanocyte protein PMEL;Melanocyte protein Pmel 17;Melanocytes lineage-specific antigen GP100;Melanoma-associated ME20 antigen;P1;P100;P26;PMEL17;Premelanosome protein;Secreted melanoma-associated ME20 antigen;SI;SIL;SILV;Silver locus protein homolog
