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Background
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration.
Product overview
Product Name
LIM and calponin homology domains-containing protein 1
Code
E5580Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.13ng/L
Reactivity
Human
Detection range
5.13ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
LIM and calponin homology domains-containing protein 1;LIMCH1;LIMCH1A;LMO7B
