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Background
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Product overview
Product Name
Cyclin-Y
Code
E5142Hu
Assay type
Sandwich
Size
96 test
Sensitivity
4.39ng/L
Reactivity
Human
Detection range
4.39ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
C10orf9;CBCP1;CCNX;CCNY;CFP1;Cyclin box protein 1;Cyclin fold protein 1;cyclin-X;Cyclin-Y;Cyc-Y
