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Background
11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. It belongs to the family of short-chain dehydrogenases.
Product overview
Product Name
Corticosteroid 11-beta-dehydrogenase isozyme 1
Code
E5120Hu
Assay type
Sandwich
Size
96 test
Sensitivity
14.25ng/L
Reactivity
Human
Detection range
14.25ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
11-beta-HSD1;11-beta-hydroxysteroid dehydrogenase 1;11-DH;Corticosteroid 11-beta-dehydrogenase isozyme 1;CORTRD2;HDL;HSD11;HSD11B;HSD11B1;HSD11L;Short chain dehydrogenase/reductase family 26C member 1
