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Background
NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097).
Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097).
Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).
Product overview
Product Name
Aldehyde dehydrogenase family 1 member A3
Code
E4919Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.31ng/L
Reactivity
Human
Detection range
7.31ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Aldehyde dehydrogenase 6;Aldehyde dehydrogenase family 1 member A3;ALDH1A3;ALDH1A6;ALDH6;MCOP8;RALDH3;RALDH-3;Retinaldehyde dehydrogenase 3;