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Background
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).
Product overview
Product Name
Non-histone chromosomal protein HMG-14
Code
E3182Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.13ng/L
Reactivity
Human
Detection range
5.13ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
High mobility group nucleosome-binding domain-containing protein 1;HMG14;Non-histone chromosomal protein HMG-14
