BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.
Background
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876).
Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876).
Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876).
Product overview
Product Name
SPRY domain-containing SOCS box protein 2
Code
E3179Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.12ng/L
Reactivity
Human
Detection range
5.12ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Gene-rich cluster protein C9;GRCC9;SPRY domain-containing SOCS box protein 2;SPSB2;SSB2;SSB-2
