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Background
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity).
Product overview
Product Name
Tumor necrosis factor ligand superfamily member 12
Code
E2532Mo
Assay type
Sandwich
Size
96 test
Sensitivity
3.28ng/L
Reactivity
Mouse
Detection range
3.28ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Apo3l;DR;Dr3l;Dr3lg;TNF-related weak inducer of apoptosis;TNFSF12;Tumor necrosis factor ligand superfamily member 12;Tumor necrosis factor ligand superfamily member 12, membrane form;Tumor necrosis factor ligand superfamily member 12, secreted form];Twea;Tweak