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Background
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Product overview
Product Name
neuregulin-2
Code
E2291Mo
Assay type
Sandwich
Size
96 test
Sensitivity
9.95ng/L
Reactivity
Mouse
Detection range
9.95ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Divergent of neuregulin 1;Do;Don1;DON-1];Neuregulin-2;NRG2;NRG-2;NT;NTAK;Pro-neuregulin-2, membrane-bound isoform;Pro-NRG2