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Background
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Product overview
Product Name
Plasma kallikrein
Code
E2198Ra
Assay type
Sandwich
Size
96 test
Sensitivity
1.52ng/mL
Reactivity
Rat
Detection range
1.52ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Fletcher factor;Kalp1;KALP15;Kininogenin;Klk3;KLKB1;PK;Plasma kallikrein;Plasma kallikrein heavy chain;Plasma kallikrein light chain];Plasma prekallikrein