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Background
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
Product overview
Product Name
3-hydroxy-3-methylglutaryl-Coenzyme A Synthase
Code
E1834Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.048ng/mL
Reactivity
Rat
Detection range
0.048ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
3H3M;3-hydroxy-3-methylglutaryl-coenzyme A reductase;HMG-CoA reductase;HMGCS
