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Background
Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.
Maintains pro-ACR as an enzymatically inactive zymogen in the acrosome until acrosomal exocytosis (PubMed:27303034).
Partially contributes also to the assembly of acrosomal proteins to form an acrosomal granule (PubMed:27303034).
Rodent specific isoform that participates in the formation of the acrosomal granule into the center of the acrosomal vesicle during early spermiogenesis (PubMed:27303034).
In the fertilization process promotes ACR release from the acrosome during acrosomal exocytosis (PubMed:27303034).
