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Background
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Product overview
Product Name
Deoxyribonuclease-2-alpha
Code
E1103Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.048ng/ml
Reactivity
Human
Detection range
0.048ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Acid DNase;Deoxyribonuclease II alpha;Deoxyribonuclease-2-alpha;DNase II alpha;DNASE2A;DNL;DNL2;Lysosomal DNase II;R31240_2;
