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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Product overview
Product Name
Bone Morphogenetic Protein Receptor 1A
Code
E0268Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.053ng/mL
Reactivity
Rat
Detection range
0.053ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Activin receptor-like kinase 3;ALK-3;BMP type-1A receptor;BMPR 1A;BMPR1A;BMPR-1A;Bone morphogenetic protein 4 receptor;Bone morphogenetic protein receptor type-1A;CD antigen CD292;
