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Background
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Product overview
Product Name
Insulin-like Growth Factors Binding Protein 3
Code
E0289Po
Assay type
Sandwich
Size
96 test
Sensitivity
14.21ng/ml
Reactivity
Porcine
Detection range
14.21ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
IBP-3;IGF-binding protein 3;IGFBP 3;IGFBP3;IGFBP-3;Insulin-like growth factor-binding protein 3
