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Background
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5′ splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. [Isoform 2]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
Product overview
Product Name
U1 Small Nuclear Ribonucleoprotein 70 Kda
Code
E2550Mo
Assay type
Sandwich
Size
96 test
Sensitivity
5.31ng/L
Reactivity
Mouse
Detection range
5.31ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
SNRNP 70;SNRNP70;U1 small nuclear ribonucleoprotein 70 kDa;U1 snRNP 70 kDa;U1-70K
