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Background
Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Product overview
Product Name
Multidrug Resistance Protein 3
Code
E2270Mo
Assay type
Sandwich
Size
96 test
Sensitivity
9.07ng/L
Reactivity
Mouse
Detection range
9.07ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ABCB1B;ATP-binding cassette sub-family B member 1B;ATP-dependent translocase ABCB1;CD antigen CD243;Multidrug resistance protein 1B;P-glycoprotein 1;Phospholipid transporter ABCB1
