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Background
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
Product overview
Product Name
Sh3Kbp1 Binding Protein 1
Code
E7316Hu
Assay type
Sandwich
Size
96 test
Sensitivity
12.14ng/L
Reactivity
Human
Detection range
12.14ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
SETA-binding protein 1;SH3KBP1-binding protein 1;SHKBP 1;SHKBP1
