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Background
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed: 20025746). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).
Product overview
Product Name
Transmembrane Protein 119
Code
E6313Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.25ng/L
Reactivity
Human
Detection range
9.25ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
OBIF;Osteoblast induction factor;TMEM 119;TMEM119;Transmembrane protein 119
