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Background
Regulates voltage-gated potassium Channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down Channel inactivation by precluding Channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Product overview
Product Name
Leucine-Rich Glioma-Inactivated Protein 1
Code
E5562Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.021ng/mL
Reactivity
Human
Detection range
0.021ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Epitempin-1;Leucine-rich glioma-inactivated protein 1;LGI 1;LGI1
