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Background
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium Channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
Product overview
Product Name
Endoplasmic Reticulum Resident Protein 44
Code
E5238Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.33ng/L
Reactivity
Human
Detection range
9.33ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Endoplasmic reticulum resident protein 44;ER protein 44;ERP 44;ERP44;Thioredoxin domain-containing protein 4
